Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQNETRTLQLDPHLHIEAYRFKGIMQKFPNHFHDYYVIGFIEKGQRYLACQDQEYIINPGDLLLFNPRDTHSCEQIDGRTLDYRCINVMPDIMEKAVKEITGSGHLPYFSQHVLFRHELTASLQELHILISEEKQALRKEELFLHLLEELIRHYSDVTFLSSVPEPSDEVKMVCEFLEEHYAENVTLNDLSELTGWSKYHLLRSFTKQKGITPNSYMETIRINQAKKLLEQGVRPIDAAFQ-TGFSDQSHMTKFFKRQVGLTPKQYMKIFEKELHR 4FE7 Chain:A ((270-406)) -----------------------------------------------------------------------------------------------------------------------------LHRLLDKEEMPLQR--ILVPPVRVIERRSTD---YRSLTDPA--VIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMIHAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDV-------

General information: TITO was launched using: RESULT: Template: 4FE7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 404 -47964 -118.72 -352.68 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -118.72 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.547

(partial model without unconserved sides chains): PDB file : Tito_4FE7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FE7-query.scw PDB file : Tito_Scwrl_4FE7.pdb: