Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDFMNFFILGADLPTLGGVKGWASDVVIQFITIVVMFIAAKNLMKLKMGGIIFVCCIGSAVTWVIKH-----WSEFSGWI--NALMEKL-- 1V1C Chain:A ((1-68)) --IFDIYVVTADYLPLGA---------------------EQDAITLREGQYVEVLDAAHPLRWLVRTKPTKSSPSRQGWVSPAYLDRRLKL

General information: TITO was launched using: RESULT: Template: 1V1C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 192 -42340 -220.52 -717.63 target 2D structure prediction score : 0.34 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -220.52 2D Compatibility (Sec. Struct. Predict.) : 0.34 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.200

(partial model without unconserved sides chains): PDB file : Tito_1V1C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V1C-query.scw PDB file : Tito_Scwrl_1V1C.pdb: