Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDNDKFKEELAKLPEVDPMTKMLVQNIFSKHGVTKDKMKKVSDEEKEMLLNLVKDLQAKSQALIENQKKKKEEAAAQEQKNTKPLSRREQLIEQIRQRRKNDNN 2Y9Y Chain:B ((423-509)) --------------------------------GIQTQQVPRYTIEGVDNTINQFKKLCSLIQSRYEIRSKKKHFVKQLKEGKKPDLSRKLEILKEIKAELKN---

General information: TITO was launched using: RESULT: Template: 2Y9Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 70 4560 65.14 65.14 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain B : 0.69 3D Compatibility (PKB) : 65.14 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.582

(partial model without unconserved sides chains): PDB file : Tito_2Y9Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y9Y-query.scw PDB file : Tito_Scwrl_2Y9Y.pdb: