Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKYGIVLFPSKKLQDLANSYRKRYDPS--YSLIPPHLTLRASFECAEEKADQLVSHLRNIAKESHPLVLKMTKYSSFAPVNNVIYIKAEPTEELKTLNEKLYTGVLAGEQEYNFVPHVTVGQ-NLSDDEHSDVLGQLKMQ---EVSHEEIVDRFHLLYQLE-N---GSWTVYETFLLGRGE 1JH6 Chain:A ((7-181)) DVYSVWALPDEESEPRFKKLMEALRSEFTGPRFVPHVTVAVSAYLTA---DEAKKMFESACDGLKAYTATVDRVSTGTFFFQCVFLLLQTTPEVMEAGEHCKNHFNCS-TTTPYMPHLSLLYAELTEEEKKNAQEKAYTLDSSLDGLSFRLNRLALCKTDTEDKTLETWETVAVCNLNP--

General information: TITO was launched using: RESULT: Template: 1JH6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 786 -100291 -127.60 -607.82 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -127.60 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_1JH6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JH6-query.scw PDB file : Tito_Scwrl_1JH6.pdb: