Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLNDKTAIVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIAVKADVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMKEDEWDDVININLKGVFNCTKAVTRQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASRNITVNAIAPGFISTDMTDKLAKDVQDEMLKQIPLARFGEPSDVSSVVTFLASEGARYMTGQTLHIDGGMVM 3TZC Chain:A ((10-249)) -LEGKVALVTGASRGIGKAIAELLAERGAKVI-GTATSESGAQAISDYLGDNG-KGMAL--NVTNPESIEAVLKAITDEFGGVDILVNNAGITR----MRMKEEEWSDIMETNLTSIFRLSKAVLRGMMKKRQGRIINVGSVV------------AAKAGVIGFTKSMAREVASRGVTVNTVAPGFIETDM-----DEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGETLHVNGGMY-

General information: TITO was launched using: RESULT: Template: 3TZC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1179 -129245 -109.62 -590.16 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -109.62 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.520

(partial model without unconserved sides chains): PDB file : Tito_3TZC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TZC-query.scw PDB file : Tito_Scwrl_3TZC.pdb: