Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRFILVL-SFLSIIVAYPIQTNASPMPCSVILEPVDKNLKNAKGVALIYKVQLNPPSAARTNISILAVHLPAPSSFGNYDSYEGFATKPGEISWRFKLYPTPEEESPSWAGRIDTISAEMKNVKVQVRLSNSSTQKLG---------PSILTKNIESCY--------- 3H05 Chain:B ((1-177)) MKKIAIFGSAFNPPSLGHKSVIESLSHFDLVLLEPSINMLDYPIRCKLVDAFIKDMG---LSNVQRSDLEQALYVT--TYALLEKIQEIYPTADITFVIGPDNFFKFAKFYK-AEEITERWTVMACPEKVSTDIRNALIEGKDISTYTTPTVSELLLNEGLYRETLSGK

General information: TITO was launched using: RESULT: Template: 3H05.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 665 -11233 -16.89 -78.00 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain B : 0.63 3D Compatibility (PKB) : -16.89 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.341

(partial model without unconserved sides chains): PDB file : Tito_3H05.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3H05-query.scw PDB file : Tito_Scwrl_3H05.pdb: