Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVIKGLTAGLIFLFLCACGGQQIKDPLNYEVEPFTFQNQDGKNVSLESLKGEVWLADFIFTNCETICPPMTAHMTDLQKKLKAENIDVRIISFSVDPENDKPKQLKKFAANYPLSFDNWDFLTGYSQSEIEEFALKSFKAI-VKKPEGEDQVIHQSSFYLVGPDGKVLKDYNGVENTPYDDIISDVKSASTLK 3ME7 Chain:A ((12-161)) -----------------------------------TLVDSYGNEFQLKNLKGKPIILSPIYTHCRAACPLITKSLLKVIPKLGTPGKDFWVITFTFDPK-DTLEDIKRFQKEYGIDGKGWKVV----KAKTSEDLFKLLDAIDFRFMTAGNDFIHPNVVVVLSPELQI-KDYIYGVNYNYLEFVNALRLAR---

General information: TITO was launched using: RESULT: Template: 3ME7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 703 -62082 -88.31 -416.66 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -88.31 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.457

(partial model without unconserved sides chains): PDB file : Tito_3ME7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ME7-query.scw PDB file : Tito_Scwrl_3ME7.pdb: