Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEEYQVKIDTFEGPLDLLLHLINRLEIDIYDIPVAKITEQYLLYVHTMRVLELDIASEYLVMAATLLSIKSRMLLPKQEEELFEDELLEEEDPREELIEKLIEYRKYKDAAKDLKEREEERQKSFTKPPSDLSEYAKEVKQSEQKLSVTVYDMIGAFQKVLKRKKINRPMETTITRQDIPIEARMNEIVHSLKSR---GTRINFMDLFPY--EQKEHLVVTFLAVLELMKNQLVLIEQEHNFSDIYITGSESIHGA 1W1W Chain:E ((40-116)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KAIVQMAKILRKELSEEKEVIFTDVLKSQA--KREASRGFFDILSLATEGCIGLSQTEAFGNIKIDAKPAL---

General information: TITO was launched using: RESULT: Template: 1W1W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain E - contact count / total energy / energy per contact / energy per residue : 182 -4213 -23.15 -65.83 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain E : 0.59 3D Compatibility (PKB) : -23.15 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.676

(partial model without unconserved sides chains): PDB file : Tito_1W1W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1W1W-query.scw PDB file : Tito_Scwrl_1W1W.pdb: