Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLITPDELKSYSVFESVKTRPDELLKQDILEATADIILKVGHDFSDAEYIPLPETVRLALLKLSQFYALINGDESIIKGYTTEKIGDYSYTLGDGSSLQKPDVYALIKDYVKPADPDLEGIEAKVRMRSI---- 2KCK Chain:A ((1-112)) ----------------MVDQNPEEYYLEGVLQYDAGNYTESIDLFEKAIQLD-PEESKYWLMKGKALYNLERYEEAVDCYNYVINVIEDEYN----KDVWAAKADAL--RYIEGKEVEAEIAEARAKLEHHHHHH

General information: TITO was launched using: RESULT: Template: 2KCK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 360 -4863 -13.51 -45.02 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -13.51 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.227

(partial model without unconserved sides chains): PDB file : Tito_2KCK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2KCK-query.scw PDB file : Tito_Scwrl_2KCK.pdb: