Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNQGSPQLVSLVDPYVYQTIKKLIGSRFVIQTVRDT-VRGRLIDVKPD-HITIEGAR---------NSVCLIRIQHMISVTPDYSERV 1I8F Chain:A ((12-79)) ----------------LGATLQDSIGKQVLVKLRDSHEIRGILRSFDQHVNLLLEDAEEIIDGNVYKRGTMVVRGENVLFISPV-----

General information: TITO was launched using: RESULT: Template: 1I8F.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 184 -4026 -21.88 -70.63 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -21.88 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.660

(partial model without unconserved sides chains): PDB file : Tito_1I8F.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1I8F-query.scw PDB file : Tito_Scwrl_1I8F.pdb: