Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTFKLVDLNVERVDKEEQSIEQFPLIDGLIINKEDGENHWLIEALVQKEHLSFFEQLQNSQSEAKVFVTITKKSNRPAQLTAAVKNIVKLEESIQVLLYGQMVTRKQQGTETILESLVKEGYTGTKLIEAFKQKL 4QXZ Chain:A ((1-133)) MKTFKAVRFQIVNEHG---RIIEYELEDGVIINKEESGTGWLLEIVISNEHYETFKEYQDNEQLLDIRVVITRPANDPALFESTVKSIKNFKTTMSIVFECHIYTLRQQYAESLLEQLIDDGLSGEELKKSFNRMM

General information: TITO was launched using: RESULT: Template: 4QXZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 507 -76812 -151.50 -577.53 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -151.50 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_4QXZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QXZ-query.scw PDB file : Tito_Scwrl_4QXZ.pdb: