Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------------------MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLY--LAVYPVTLALKKKQSKPYQKWMCYYGFPTCCFLMISVFHKPPLIWVGVSLLP---------LFLIHMYF-------ARRKNERALLNDVAGVLFFCSG--GFASCWLGMGT------LDGWAWFIFLQSALFFIGSSFYVKSVIRERK-NRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFH---GRDWPVKTIGILEIVNACFFLAVMCLFITR 1JQE Chain:A ((13-292)) GKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELV---AKISNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCN----FNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA-----

General information: TITO was launched using: RESULT: Template: 1JQE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 985 -64690 -65.67 -284.98 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -65.67 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.246

(partial model without unconserved sides chains): PDB file : Tito_1JQE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JQE-query.scw PDB file : Tito_Scwrl_1JQE.pdb: