Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKCNKMNRVQLKEGSVSMTL 1KLR Chain:A ((5-11)) --CQYCEFR-----------

General information: TITO was launched using: RESULT: Template: 1KLR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1 -247 -247.00 -35.29 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.48 3D Compatibility (PKB) : -247.00 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.48 QMean score : 1.105

(partial model without unconserved sides chains): PDB file : Tito_1KLR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KLR-query.scw PDB file : Tito_Scwrl_1KLR.pdb: