Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQFFLRYAYAPLFWSGFIGLATWQVGYRQASHAWLVALFLGALGLSFLAERRLPYQPRWNRPHADRLRDVLHASVNESLNALGILALPLLAGVLGFWPVWPQAWPLWLQLLLAIVLADLGITLVHYASHRSALLWRLHAVHHSVQRLYGFNGLMKHPLHLGLEAL-GGTLPLLLLG---VPQTVAALLAFAIGIQLLLQHSNVDMRIGGLRHVFAWAPLHRLHHIRYGRAGDVNFALFFSVWD-RLLGTALHR-PDYRLDSTDMGIGDQPDYPRDYAGQLLAPFRDLPRSRHVPQPPEGLGRSAGQA 2I76 Chain:A ((4-259)) -------------VLNFVGT--------------------GTLTRFFLECLKIGYILSRSIDRARNLAEVYGGKAATLEKHPEVVFVIVPDR---------------YIKTVANHLNLGDAVLVHCSGFLSSEIFKKSGRASIHPNFSFLEK----------ALEMKDQIVFGLEGDERGLPIVKKIAEEISGKYFVIPSEKKKAYHLAAVIASNFPVALAYLSKRIYTLLGLDEPELLIHTLMKGVADNIKKMRVECSLTGPVKRGDWQVVEEERREYEKIF-GNTVLYDEIVKLLREVAESERR-

General information: TITO was launched using: RESULT: Template: 2I76.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -104383 for 1690 contacts (-61.8/contact) + 2D Compatibility (PS) -24859 + (NN) 5261 + (LL) 5960 1D Compatibility (HY) 400 + (ID) 1200 Total energy: -118821.0 ( -70.31 by residue) QMean score : 0.034

(partial model without unconserved sides chains): PDB file : Tito_2I76.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I76-query.scw PDB file : Tito_Scwrl_2I76.pdb: