Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFKPFVGVALAALFAVSAVAHAEDAGPVVIKFSHVVSDDTPKGKGALLFKKLAEERLPGKVKVEVYPNSTLFGDADEIEALRANKVQMLATSLSKFEPYTKQLQVFDLPFLFDDLE-ALKRFQKRDKSRELLRSMAKH-GIYGLAYWNNGMKQLSATRELHRPDDAKGLVFRIQPSSVLEAQFAMLGATAKQLSYAETLKAMQAGSVQGTENTWSNLAGQKIDSVQPYITETNHGALSYMLITSSAFWTGIPYQTRTELESIVDEVTLVVNKEAEALNQKEREHLLAAGKSRLVSLSAEEHEAWRNAMKPLWKNYEAQIGSDVLRAAQVVNRKR 2XWI Chain:A ((5-291)) -----------------------------LKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRAMLKQLKDGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSIADMKGLKLKVPNAATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYLVSNETYKELP----EDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTG--------------

General information: TITO was launched using: RESULT: Template: 2XWI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -59710 for 2464 contacts (-24.2/contact) + 2D Compatibility (PS) -30451 + (NN) -14487 + (LL) 4448 1D Compatibility (HY) -14000 + (ID) 3250 Total energy: -117450.0 ( -47.67 by residue) QMean score : 0.491

(partial model without unconserved sides chains): PDB file : Tito_2XWI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XWI-query.scw PDB file : Tito_Scwrl_2XWI.pdb: