Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDITFNTGLMGSGKSKKLID-DYLIDPK-EKVALSVSLTEDTFSRG---KIESRDGRSLRSINLNRDQFKQNISLLEIIIFMTNTQTIYIDESQFLPKETVEKFVSLSESYHVPIHFYGLDLTFTGELFDSSSHLLTILPSENINRISRGCEASKCSK-IAQYNARIVDGKVSRSGETFVEEKSY-YLALCSDHYYNDEKII 4UXH Chain:A ((5-180)) GRIELIIGPMFAGKTTELMRRVKREIHARRSCFVIK---YSKDTRYDEHNVA----LMLRAQAAVS-Q---LTEVR---DTWKRFDVLAIDEGQFFSD-LVDFCNTAAD-AGKVVMVSALDGDYRRKPFGQICELVP--YCEAVDKLTAVCMM--CHEQPACFTRRTVNV-----EQQELIGGADMYIATCRECYSK-----

General information: TITO was launched using: RESULT: Template: 4UXH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 827 -79346 -95.94 -480.88 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -95.94 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.284

(partial model without unconserved sides chains): PDB file : Tito_4UXH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UXH-query.scw PDB file : Tito_Scwrl_4UXH.pdb: