Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNWMEFISSIVKSIIWPVAIIILVFKLKQPVSNLISTLAKIKYKDWEFEFTIDQKLDKISFQLNKENQYGTDDQNLKDSLNLESNSEITEETHSHYNEKTSIKGDNDLLLKMEMIRLYGAVKNLYEKVSEKDDAADKSQGIGMLYMVDYLKRHKILNDSFAESLLDIMNIVHDLEKSHISQSYIMNKFFWNVDKSVKRLMEITSNYVAENTAGETSN 1XLX Chain:A ((210-299)) ----------------------------------------------------------------------------------------------------------DMVLATDMSKHMSLLADLKTMVETK-----KVTSSGVLLLDNYTDRIQVLRNMV--HCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEIS--------------

General information: TITO was launched using: RESULT: Template: 1XLX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 136 3468 25.50 38.53 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 25.50 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.171

(partial model without unconserved sides chains): PDB file : Tito_1XLX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XLX-query.scw PDB file : Tito_Scwrl_1XLX.pdb: