Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSKKKQIKLGVFLAGTGHHVASWRHPDAPSDASMNLDYFKELAKTAERGKLDMLFLADSLSIDSKSHPNVLTRFEPFTLLSALAQVTSKIGLTAT-ASTTYSEPFHIARQFASLDHLSNGRAGWNVVTSSIESTALNFSGEKHLEHHLRYQRAEEFVEIVKGLWDSWEEDAFIRNKETGEFFDK-EKMHELNHKGEYFSVRGPLNVSRTPQGQPVIIQAGS-SGDGKALAAKTAEVIFTAQNHLESAQEFYQSIKEQAAEFGRDPEKIAIMPGIFPIIADTEEAAQAKYKELQDLIIP-SVGLQILQNYLGGIDLSAYPLDGPLPKLDAEASNAVKS---RFKLVQEMA---ERDNMTIRELYKYVAGSRGHHIFVGTPEQLADKMQEWVDTKACDGFNIMPPLLPEGIEVFVDQVVPILQERGVFRKEYEGTTLREHFGLEKPVNRYAK 5DQP Chain:A ((4-428)) -----RRMYLVSWLNSSGVLPNSWNEGRGNRARIFDLENYIRSAEIARRGRIDAFFLADQPQLTPNPKVRPEYPFDPIVLAAAITGRVPDIG-GIVTASTSFSLPYTLARQIASVNLLSGGRIGWNAVTTANPAVAANYGAAI-ATHDNRYERAEEFLEVVHGLWNSW---KFPWDEAIGPNPNPFGEVMPINHEGKYFKVAGPLNVPLPPY-GPPVVVQAGGSDQGKRLASRFGEIIYAFLGSKPAGRRFVAEARAAARAQGRPEGSTLVLPSFVPLIGSTEAEVKRLVAEYEAGLDPAEQRIEALSKQLG-IDLERINVDQVLQE--KDF-NLPKESATPIGILKSMVDVALDEKLSLRQLA------LRMRLIAGTPDQVADRLIDWWQDEAADGFVINAPLLPDALEIFVDQVVPILQSRGVFPRSYTESTLRERLGLPRNP-----

General information: TITO was launched using: RESULT: Template: 5DQP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2153 -24468 -11.36 -58.96 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -11.36 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.522

(partial model without unconserved sides chains): PDB file : Tito_5DQP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DQP-query.scw PDB file : Tito_Scwrl_5DQP.pdb: