Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPR---ELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQGFN-LKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKG-VSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST 4BKZ Chain:A ((12-264)) ---------YELHETIGTG--AKVKLACHILTGEMVAIKIMDK-----NTL---LPRIKTEIEALKNLRHQHICQLYHVLETAN-KIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC-A--------------SLAYAAPELIQG----GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSIL--LLQQMLQVDPKKRISMKNLLNHPWIMQD

General information: TITO was launched using: RESULT: Template: 4BKZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -137944 for 1711 contacts (-80.6/contact) + 2D Compatibility (PS) -23649 + (NN) -10353 + (LL) 1388 1D Compatibility (HY) -27200 + (ID) 4950 Total energy: -202708.0 ( -118.47 by residue) QMean score : 0.398

(partial model without unconserved sides chains): PDB file : Tito_4BKZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BKZ-query.scw PDB file : Tito_Scwrl_4BKZ.pdb: