Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMFNFPNTRLRRRRSSKWVRNLTSESALSVNDLIFPLFVHDREETTELVSSLPGMKCYSIDGLVSIAQEAEDLGINAVAIFPVVDSKLKSENAEEAYNSDNLICKAIRAIKLKVPGIGIIADVALDPYTTHGHDGILKSNQIDVENDKTVSILCKQALALAKAGCNIVASSDMMDGRVGRIRKVLDDNNLQD-VSILSYAVKYCSSFYAPFRQIVGSCVSSNSIDKSGYQMDYRNAREAICEIEMDLNEGADFIMVKPGMPYLDIIKMASDEF-NFPIFAYQVSGEYAMIKAATNNGWLDYDKVIYESLVGFKRAGASAIFTYAALDVAKNLR 1E51 Chain:A ((21-318)) ----------------------TATTTLNASNLIYPIFVTDVPDDIQPITSLPGVARYGVKRLEEMLRPLVEEGLRCVLIFGVPSRVPKDERGSAADSEESPAIEAIHLLRKTFPNLLVACDVCLCPYTSHGHCGLLS--GA-FRAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKEALMAHGLGNRVSVMSYSAKFASCFYGPFRDAAKS--SPAFGDRRCYQLPPGARGLALRAVDRDVREGADMLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAVLEAMTAFRRAGADIIITYYTPQLLQWLK

General information: TITO was launched using: RESULT: Template: 1E51.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -214369 for 2510 contacts (-85.4/contact) + 2D Compatibility (PS) -32498 + (NN) -11567 + (LL) 1724 1D Compatibility (HY) -20000 + (ID) 5550 Total energy: -282260.0 ( -112.45 by residue) QMean score : 0.544

(partial model without unconserved sides chains): PDB file : Tito_1E51.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1E51-query.scw PDB file : Tito_Scwrl_1E51.pdb: