Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVIDDFEKLDIRTGTIVKAEEFPEARVPAIKLVIDFGTEIGIKQSSAQITKRYKPEGLINKQVIAVVNFPPRRIAGFKSEVLVLGGIPGQGDVVLLQPDQPVPNGTKIG 3G48 Chain:B ((4-112)) MANFEDFLTLDLRIGTVTHAEEF-----PAIRLEIDFG-ELGMKQSSAQITKRYNPEDLIGQQIVAVVNFPPKRVAGFKSEVLVLGGVPEAGDVVLLQPNMELPNGTKIS

General information: TITO was launched using: RESULT: Template: 3G48.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 474 -40439 -85.31 -388.84 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain B : 0.90 3D Compatibility (PKB) : -85.31 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.486

(partial model without unconserved sides chains): PDB file : Tito_3G48.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3G48-query.scw PDB file : Tito_Scwrl_3G48.pdb: