Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTIKVKSAHKDGQIKLEDLDVVCNKLCKRNNSVLFKLEKYLNKKLLSDPELTEIRDTILTVSGELSRLRDNLVTDGDSNEGLQ 1T2E Chain:A ((198-232)) -----------------------------------IPLQEFINNKLISDAELEAIFDRTVNTALEIVNLH--------------

General information: TITO was launched using: RESULT: Template: 1T2E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 28 -7265 -259.46 -207.57 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -259.46 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.516

(partial model without unconserved sides chains): PDB file : Tito_1T2E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1T2E-query.scw PDB file : Tito_Scwrl_1T2E.pdb: