Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNMDFNLFMNDIVRQARQEITAAGYTELKTAEEVDEALTKKGTTLVMVNSVCG-CAGGIARPAAYHSVHYDKRPDQLVTVFAGQDKEATARARDYFEGYPPSSPSFAILKDGKIMKMVERHEIEGHEPMAVVAKLQEAFEEYCEEV 3WGD Chain:A ((6-111)) -------------------------KHLYTADMFTHGIQSAAHFVMFFAPWCGHCQR--LQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQG--VRGYPTLKLFKPGQEAVKY----QGPRDFQTLENWMLQTL-------

General information: TITO was launched using: RESULT: Template: 3WGD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 436 -4036 -9.26 -38.44 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -9.26 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.485

(partial model without unconserved sides chains): PDB file : Tito_3WGD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WGD-query.scw PDB file : Tito_Scwrl_3WGD.pdb: