Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITQLYRERTAADLKNRISK-------VLLNGNETEIVELTIQ----------GAVVT----VLTQREEDIKHIKSVQILDDQNNVITERTTDLDVSNNRTLDFRITFEVV 1OI0 Chain:A ((1-121)) GSSMKISRGLLKTILEAAKSAHPDEFIALLSGSKDVMDELIFLPFVSIGMKVFGTVHSHPSPSCRPSEEDLSLFTR---FGKYHIIVCYPYDENSWKCYNRKGEEVELEVV

General information: TITO was launched using: RESULT: Template: 1OI0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 319 -231 -0.72 -2.65 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -0.72 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.369

(partial model without unconserved sides chains): PDB file : Tito_1OI0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OI0-query.scw PDB file : Tito_Scwrl_1OI0.pdb: