Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYCPQCGHQ-TDG-GNFCEKCGSPLPGQSGHQHAAQTGAAAKQAAKQFGSFVLSVLKRPYQECKATGGEQLISAIITMVLFSLLTPLMFYILFSDGPGSVSFTAIFLEPTIYFILFLFGLHACIFFALKIAGNQVSFKDSFSRFGAFLIPFTAILILALFFFLLHTDICFTILAVGLIGAFFAIPPAMLSSYQHSYKGKVDFIYSTIVIYLIICVTFQLIIEHYVKEIFRYMLF 2CON Chain:A ((16-42)) LRCHGCFKTTSDMNRVFCGHCGNKTLK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2CON.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 62 -1982 -31.96 -79.26 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.39 3D Compatibility (PKB) : -31.96 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.39 QMean score : 0.851

(partial model without unconserved sides chains): PDB file : Tito_2CON.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CON-query.scw PDB file : Tito_Scwrl_2CON.pdb: