Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --MKVQHKKELKFYCIVTIPSAFVVLTVISFLLQEITFPV------------TASAFLNASWHNLLFLI---PFGLFFYPVHIWMKREFGRWNDTEKKRG-- 2IDA Chain:A ((1-102)) MTMGCRHVAGIRTVTPSALGCEECLKIGSPWVHLRICRTCGHVGCCDDSPHKHATRHFHATGHPIIEGYDPPEGWGWCYVDEVMFDLSDRMTPHNGPIPRYV

General information: TITO was launched using: RESULT: Template: 2IDA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 389 -32903 -84.58 -396.42 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -84.58 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.056

(partial model without unconserved sides chains): PDB file : Tito_2IDA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IDA-query.scw PDB file : Tito_Scwrl_2IDA.pdb: