Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDGFPGRGAVITGGASGIGLATGTEFARRGARVVLGDVDKP-GLRQAVNHLRAE-GFDVHSVMCDVRHREEVTHLADEAFRLLGHVDVVFSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIHTVEAFLPRLLEQGTGGHVVFTASFAGLVPNAGLGAYGVAKYGVVGLAETLAREVTADGIGVSVLCPMVVETNLVANSERIRGAACAQSSTTGSPGPLPLQDDNLGVDDIAQLTADAILANRLYVLPHAASRASIRRRFERIDRTFDEQAAEGWRH 3W8E Chain:A ((2-193)) ---LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLNADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHGTAAALPIMQKQGWG-RIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCNAICPGWVRTPLV---------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3W8E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -154395 for 1586 contacts (-97.3/contact) + 2D Compatibility (PS) -20550 + (NN) -4967 + (LL) 4696 1D Compatibility (HY) -9600 + (ID) 3400 Total energy: -188216.0 ( -118.67 by residue) QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_3W8E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3W8E-query.scw PDB file : Tito_Scwrl_3W8E.pdb: