Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVKISQTADVQRFFEEASGQLNERGDPRTKALVRRILDDTAKLIEEMQVTPDEFWKAVDYLNRLGSRQEAGLLAAGLGLEHYLDLLLDAQDAEAGLTGGTPRTIEGPLYVAGAPLSDGEARMDDGRDA-GTVMFLQGRVSGPDGQPLAGAIVDVWHANTQGTYSYFDSS--QSEYNLRRRIRTDADGRYRARSIVPSGYGCPSDGPTQELLDRLGRHGQRPAHIHFFVSAPGHRHLTTQINLAGDRYLWDDFAYATRDGLIGDLRFNDDPAAARDRGVEGGRFAELDFDFQLQASPAPAAERRSQRPRALQG 1DMH Chain:A ((3-311)) --VKIFNTQDVQDFLRVASGLEQEGGNPRVKQIIHRVLSDLYKAIEDLNITSDEYWAGVAYLNQLGANQEAGLLSPGLGFDHYLDMRMDAEDAALGIENATPRTIEGPLYVAGAPESVGYARMDDGSDPNGHTLILHGTIFDADGKPLPNAKVEIWHANTKGFYSHFDPTGEQQAFNMRRSIITDENGQYRVRTILPAGYGCPPEGPTQQLLNQLGRHGNRPAHIHYFVSADGHRKLTTQINVAGDPYTYDDFAYATREGLVVDAVEHTDPEAIKANDVEG-PFAEMVFDLKLTRLVDGVDNQVVDRPRLAV-

General information: TITO was launched using: RESULT: Template: 1DMH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -45019 for 2271 contacts (-19.8/contact) + 2D Compatibility (PS) -33458 + (NN) -19565 + (LL) -84 1D Compatibility (HY) -24400 + (ID) 8550 Total energy: -131076.0 ( -57.72 by residue) QMean score : 0.589

(partial model without unconserved sides chains): PDB file : Tito_1DMH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DMH-query.scw PDB file : Tito_Scwrl_1DMH.pdb: