Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNQSSTPGFLLLGFSEHPGLERTLFVVVLTSYLLTLVG---NTLIILLSALDPKLHSPMYFFLSNLSFLDL-----CFTTSCVPQML-VNLWGPKKTISFLDCSVQIFIFLSLGTTECILLTVMAFDRYVAVCQPLHYATIIHPRLCWQLASVAWVIGLVESVVQTPSTLHLPFCPDRQVDDFVCEVPALIRLSC-------EDTSYNEIQVAVASVFILVVPLSLILVSYGAITWAVLRINSAKGRRKAFGTCSSHLTVVTLFYSSVIAVYLQPKNPYA-------QERGKFFG-------LFYAVGTPSLNPLIYTLRNKEVTRAFRRLLGKEMGLTQS 2I35 Chain:A ((45-312)) --------------------------------FLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPT------GCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVA-FTWVMALA--------------CAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQL---VFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNDDE-

General information: TITO was launched using: RESULT: Template: 2I35.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -163685 for 1756 contacts (-93.2/contact) + 2D Compatibility (PS) -23704 + (NN) 1176 + (LL) 4088 1D Compatibility (HY) -23200 + (ID) 3350 Total energy: -208675.0 ( -118.84 by residue) QMean score : 0.221

(partial model without unconserved sides chains): PDB file : Tito_2I35.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I35-query.scw PDB file : Tito_Scwrl_2I35.pdb: