Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKHITTVVIWKILRCLSLVFGVSILTFILLKQSPVDPVMASVNYDTSLTPVQYKAIAHHYGLDKPAPVQYFIWLKNFIQGHLGTSLVYRQPVIDIIRSRAGASFILMGLSWVLSGLIGFILGTLSAFHQGKLLDRIVRWFSYLQISVPTFWIGLIFLLIFSVQLGWFPIGISSPIGTLSQDITLADRIKHLILPVFTLSILGIANVTLHTRTKMMSVLSSEYVLFARARGETEWQIFKNHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGLGSTLTEAGLKS-DTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV 2ONK Chain:C ((24-275)) MRLLFSALLALLSSIILLFVLLPVAATVTLQLFNFDEFLKAAS---------------------------------------------DPAVWKVVLTTYYAALISTLIAVIFGTPLAYILARKSFPG-----KSVVEGIVDLPVVIPHTVAGIALLVVFGSS-GL--IGSFSPLKFVDALPGIVVAMLFVSVPIYINQAKEGFAS-----------VDVRLEHVARTLGSSPLRVFFTVSLPLSVRHIVAGAIMSWARGISEFGAVVVIAYYPMIAPTLIYERYLSEGLSAAMPVAAILILLSLAVFVALRIIVG----------

General information: TITO was launched using: RESULT: Template: 2ONK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -176403 for 1861 contacts (-94.8/contact) + 2D Compatibility (PS) -25813 + (NN) -5948 + (LL) 5588 1D Compatibility (HY) -15200 + (ID) 1800 Total energy: -219576.0 ( -117.99 by residue) QMean score : 0.142

(partial model without unconserved sides chains): PDB file : Tito_2ONK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ONK-query.scw PDB file : Tito_Scwrl_2ONK.pdb: