Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSIDLTILSLKRKGIRTEKVLKNQNPDRLSHMTDKNAQPKSKEKEE 3B9W Chain:A ((8-369)) INEARLVAQYNYSINILAMLLVGFGFLMVFVRRYGFSATTGTYLVVATGLPLYILLRANGIFGHALTPHSVDAVIYAEFAVATGLIAMGAVLGRLRVFQYALLALFIVPVYLLNEWLVLDNASGLTEGFQDSAGSIAIHAFGAYFGLGVSIALTTAAQRAQPIESDATSDRFSMLGSMVLWLFWPSFATAIVPFEQMPQTIVNTLLALCGATLATYFLSALFHKGKASIVDMANAALAGGVAIGSVCNIVGPVGAFVIGLLGGAISVVGFVFIQPMLESKAKTIDTCGVHNLHGLPGLLGGFSAILIVPGIAVAQLTGIGITLALALIGGVIAGALIKLTGTTKQAYEDSHEFIHLAGPEDE

General information: TITO was launched using: RESULT: Template: 3B9W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 32 7460 233.11 158.71 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.40 3D Compatibility (PKB) : 233.11 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.40 QMean score : 0.206

(partial model without unconserved sides chains): PDB file : Tito_3B9W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3B9W-query.scw PDB file : Tito_Scwrl_3B9W.pdb: