Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPKYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEYYHHAS 4EOQ Chain:A ((3-292)) -GSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRL---TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASAL----TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV-----PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD------

General information: TITO was launched using: RESULT: Template: 4EOQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -170397 for 2252 contacts (-75.7/contact) + 2D Compatibility (PS) -30231 + (NN) -16416 + (LL) 396 1D Compatibility (HY) -36800 + (ID) 8200 Total energy: -261648.0 ( -116.18 by residue) QMean score : 0.566

(partial model without unconserved sides chains): PDB file : Tito_4EOQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4EOQ-query.scw PDB file : Tito_Scwrl_4EOQ.pdb: