Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQPYTKNWTQVTEFVMMGFAGIHEAHLLFFILFLTMYLFTLVENLAIILVVGLDHRLRRPMYFFLTHLSCLEIWYTSVTVPKMLAGFIGVDGGKNISYADCLSQLFIFTFLGATECFLLAAMAYDRYVAICMPLHYGAFVSWGTCIRLAAACWLVGFLTPILPIYLLSQLTFYGPNVIDHFSCDASPLLALSCSDVTWKETVDFLVSLAVLLASSMVIAVSYGNIVWTLLHIRSAAERWKAFSTCAAHLTVVSLFYGTLFFMYVQTKVTSSINFNKVVSVFYSVVTPMLNPLIYSLRNKEVKGALGRVFSLNFWKGQ 4LDL Chain:A ((200-355)) -------------------------------------------NVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIET--LCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPI----QMHWYRATHQEAINCYAEE----TC--------CDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKFALKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQ

General information: TITO was launched using: RESULT: Template: 4LDL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -119997 for 1062 contacts (-113.0/contact) + 2D Compatibility (PS) -16224 + (NN) -4540 + (LL) 6604 1D Compatibility (HY) -12000 + (ID) 2000 Total energy: -148157.0 ( -139.51 by residue) QMean score : 0.216

(partial model without unconserved sides chains): PDB file : Tito_4LDL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LDL-query.scw PDB file : Tito_Scwrl_4LDL.pdb: