Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA 1GIJ Chain:A ((2-291)) ----------ENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIR-----------AIREISLLKELN---HPNIVKLLDVIHT-----ENKLYLVFEHVHQDLKTFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLA-------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL--------------

General information: TITO was launched using: RESULT: Template: 1GIJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -167678 for 2032 contacts (-82.5/contact) + 2D Compatibility (PS) -27416 + (NN) -10841 + (LL) 3308 1D Compatibility (HY) -32400 + (ID) 7050 Total energy: -242077.0 ( -119.13 by residue) QMean score : 0.741

(partial model without unconserved sides chains): PDB file : Tito_1GIJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GIJ-query.scw PDB file : Tito_Scwrl_1GIJ.pdb: