Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTP-SHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV-TFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 1G5S Chain:A ((2-298)) ---------ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR------------STAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGL--------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------

General information: TITO was launched using: RESULT: Template: 1G5S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -169772 for 2064 contacts (-82.3/contact) + 2D Compatibility (PS) -28735 + (NN) -9345 + (LL) 3924 1D Compatibility (HY) -30000 + (ID) 6150 Total energy: -240078.0 ( -116.32 by residue) QMean score : 0.550

(partial model without unconserved sides chains): PDB file : Tito_1G5S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1G5S-query.scw PDB file : Tito_Scwrl_1G5S.pdb: