Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRR-VMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS 2JAV Chain:A ((7-262)) --------------------------------DYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQM-LVSEVNLLRELKHPNIVRYYDRIID--TLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRSD-----LKPANVFLDGKQNVKLGDFGLARIL-----------GTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTA--FSQKELAGKIREGKFRRIPY-RYSDELNEIITRMLNLKDYHRPSVEEILENPLILEHHHHHH

General information: TITO was launched using: RESULT: Template: 2JAV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -149487 for 1716 contacts (-87.1/contact) + 2D Compatibility (PS) -25070 + (NN) -17216 + (LL) 2176 1D Compatibility (HY) -23200 + (ID) 4400 Total energy: -217197.0 ( -126.57 by residue) QMean score : 0.522

(partial model without unconserved sides chains): PDB file : Tito_2JAV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2JAV-query.scw PDB file : Tito_Scwrl_2JAV.pdb: