Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)
Input alignment information:
| Query sequence | MKPKHYPDTISSPDFSSLEKEIIKFWQENKIFEQSV-EKRSKDNCFVFYDGPPFANGLPHYGHLLTGFIKDAFARYQTMLQKKVERRFGWDCHGLPAEMGAEKELGISGRTEIEKFGIEKFNNYCRTSVMKFSSEWEKYVNRQARWVDFHNDY-KTMDRSFMESVIWA---FKQLYDKGLVYESVRVVPYSWACETPLSNFET------RLDTAYRKKT-----SKAVTVAFELLENPQQFKQKCKLLAWTTTPWTLPSN-LALAIGKDIEYCAVSVHSSVSFQHVTLESREKETWIPLSRTG-MTEEGTETVTEDNEVSLVNNEIYIFAEDYLEKFIGHCEQNNIPYENCNTKLKADDLAGLSYKPLFNYFKG----TKNAFRVFIADYVTGEDGTGVVHTAPGFGEEDFYLCQSHDI---PAICPIDNSGRFTAEVSDLTGIHVFDTNDAIIKKLKEQGNWFKTEQYIHNYPHCWRTDTPLIYRAMPSWYVAVTKFKERMIELNKRVNWIPTHIRDGQFGKWLERAHDWSISRNRFWGTPIPIWKSDNARYPRVDVYGSIAELERDFNVKVNDLHRPFIDSLTRPNPDDPT-GKSIMRRVP-----DVFDCWFESGSVPFAQVHYPFENKEWFESN-----FPADFITEYIAQTR------GWFYTLFVLSTALFDSEPFKNCICHGVVL-------------------------DVKGQ------------------KLSKRLNNYADPMEVFDKYGSDALRFLMLSGSIVCGGNLFLNKEGSSIRDVLKNVMKPIWNSYHFFTMYANADGIKAEVCKDYKSTIDSYMIFKCFEAVESIQASMSNYNSQEACKILIDFFEVLNNWYIRRSRERFWKSNLDQDKTDAYNVLYTVFYYILRAAVPLLPLITETIWQGLKYKEISVHLADFPQLERYDSELIAKMDLVREICNSALSIRNTFNIRVRQPLGSMTVYHQSSCSFLESKPLSVVIPKFSPVIPMRDTGTQKEKKWSNAEMKTSMNEYQEMIKDEVNVKELKLVNSLEGIASLELKLNFPMLGKRIPDKVKKLVQYVKEGKWKQVDNEQVFLGNESESYIIEKDEYELLLKTNSEYSSVFGDNKGIVILNTALDDALVLEGLARDVVRLIQEARKQADFHISDRIRVIIKTEDEKIKRAINTWGEYIREQTLSLSLEINIEIGDNFYSKEYQDLIVGIELNC |
| 4CQN Chain:A ((30-797)) | -----------------IESKVQLHWDEKRTFEVTEDESKEKYYCLSML---PYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVK------------------NN---TAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLD------KLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPE------------------LAAFIDECR---------NTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGS-----------------EPDLSQQALTEKGVLFNSGEF-----------NGLDHEAA---FNAIADKLTAMGVGERKVNY---------------RLRDWGVSRQRYWGAPIPMVTLED---------GTVMPTPDD-QLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMES-SWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFAS---PADMTLEWQESGVEGA-NRFLKRVWKLVYEHTAKGDVAALNVDALTENQKAL-RRDVHKTIAKVTDDIGRRQTFNTAIAA-----IMELMN---------KLAKAPTDGEQDRA--LMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ |
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General information:
TITO was launched using:
| RESULT:
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Template: 4CQN.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
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3D Compatibility (PKB) -214680 for 5561 contacts (-38.6/contact) +
2D Compatibility (PS) -71786 + (NN) -18259 + (LL) 23944
1D Compatibility (HY) -30800 + (ID) 9650
Total energy: -321231.0 ( -57.76 by residue)
QMean score : 0.284
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