Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDREQIIALQHQRFATKKYDPNRRISEKDWEVLVEVGRLAPSSIGLEPWKMLLLKNERMKEDLKPMAWGGLSSLE----GASHFVIYLARKGVTYDSDYVKKVMHEVKKRDYDTHSRFA------------QIIKNFQENDIKLNSERSLFDWASKQTYIQMANMMMAAAMLGIDSCPIEGYDQEKVEAY--LEEKGYLNTAEFGVSVMASFGYRNQE----ITPKTRWKTEVIYEVIE 1ICV Chain:A ((3-207)) -----IISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASHVVVFCAK--TAMDDVWLKLVVDQ-----EDADGRFATPEAKAANDKGRKFFADMHRKDLHDDAE-----WMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKGYTSL------VVVPVGHHSVEDFNATLPKSRLPQNITLTEV-

General information: TITO was launched using: RESULT: Template: 1ICV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -61725 for 1314 contacts (-47.0/contact) + 2D Compatibility (PS) -20002 + (NN) -10105 + (LL) 1524 1D Compatibility (HY) -11200 + (ID) 2850 Total energy: -104358.0 ( -79.42 by residue) QMean score : 0.454

(partial model without unconserved sides chains): PDB file : Tito_1ICV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ICV-query.scw PDB file : Tito_Scwrl_1ICV.pdb: