Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLDKAVMRLSGIHKLLGLLAGLDVLQAIFIIGQAYYLSLSITGLWEGQKLSSQTVYILLFMVSYLGRHVIDYIKNRKLDDFSTAQSSLLRRQLLDKLFDLGPKVVQEQGTGNVVTMALDGVSLVENYLRLVLNKMINMSIIPWIILAYIFYLDIESGAILLIVFPLIIIFMIILGYAAQAKADKQYESYQVLSNHFLDSLRGIDTLKYFGLSKRYGKSIYQTSESFRKATMSTLKIGILSTFALDFFTTLSIAIVAVFLGLRLLNEQIYLLPALTILILSPEYFLPVRDFSSDY-HATLDGKNAFQAIQKV-----LNKTGIKGEQLVIDDWSKESHLDLENIAIAYDQKR---VVEDVTLRFRGHQKVALVGVSGSGKSSLINLLSGFLGPDKGSLKVDGREVVNLDQEDWHKQMIYIPQTPYVFEMSLRDNITFYTPNA---SDEEVIRAIHMVGLDSLLSELPDGLETRIGNGARPLSGGQAQRIALARAFLDQNRRIMVFDEPTAHLDIETELELKEKMLPLMSDRLVIFATHRLHWLNQMDVIVVMEKGRVVEVGSYQELLAKKGYLYQLKHAMGGNNV 4KSD Chain:A ((987-1271)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQGLKPNML-------EGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIA-YGDNSRVVSYEEIVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQP-HILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYFSMVSVQA----

General information: TITO was launched using: RESULT: Template: 4KSD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -160818 for 1996 contacts (-80.6/contact) + 2D Compatibility (PS) -29639 + (NN) -11312 + (LL) 25984 1D Compatibility (HY) -24400 + (ID) 4800 Total energy: -204985.0 ( -102.70 by residue) QMean score : 0.454

(partial model without unconserved sides chains): PDB file : Tito_4KSD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4KSD-query.scw PDB file : Tito_Scwrl_4KSD.pdb: