Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITLFQCLYLILFSFICYQGAAAFSHSTAASWLAAALGAAAAGLYIWNTKRVWKHCSSGLCAWIAVIQVMSVGVVLIGTDIMPVLCVIAIFAGCEGLRIGQSALQARLSDQIDKLTQAEQHANQMLIDVRSRNHDTMKHITAIKSA-Q-------PKADTQAYIQNWADQYSQYDRFLKG----------------ENAYVAGVLYDFLEKARASNVSVSLHMHTPLSSLPFSPADQVSLVGNILENALDSAAEAREKAEIKLETSLRSGLYVLTCENSTPGMDPKVLDTIYQSFGRSTKNGAHEGMGTYIIQKLVK-GAFGRLDFTYRHPIFRLEIKIPFQK 3A0R Chain:A ((130-345)) --------------------------------------------------------------------------------------------------------------------------SILGEMTARVAHEIRNPITIIGGFIMRMKKHLDDPETLKKYINIITNELSRLETIVKEILEYSKERVLEFTEFNLNELIREVYVLFEEKIRKMNIDFCFETDNEDLRVEADRTRIKQVLINLVQNAIEATGEN---GKIKITSEDMYTKVRVSVWNSGPPIPEELKEKIFS-PFFTT-------LGLSICRKIIEDEHGGKIWTENRENGVVFIFEIPKT-

General information: TITO was launched using: RESULT: Template: 3A0R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 717 -78741 -109.82 -427.94 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -109.82 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.420

(partial model without unconserved sides chains): PDB file : Tito_3A0R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3A0R-query.scw PDB file : Tito_Scwrl_3A0R.pdb: