Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTFFQFDELGTSYRNEIIGGLTTFLSMA--YILFV-NPITLALESVKDFPEALRIDQGAVFTATALASAAGCILMGLIARYPIAI-APGMGLNAFFA---FSVVLGMG-ISWQAALSGVFISGLIFVALSLTGFREKIINAIPPELKLAVGAGIGLFITFVGLQG-SGIITANPS----TLVTIGNIHSGPVLLTIFGVIVTVILMVLR-----------VN--AGVFIGMLLTAVAGMIFGLVPVPTQIIGSVPSLAPTFGQA-WI---HLPDIFSVQMLIVILTFLFVGFFDTAGTLVAVATQAGLMKENKLPRAGRALLADSSSIVIGAVLGTSTTTS-YVESSSGVAA----GA-----RSGFAAIVTGILFLLATFFSPLLSVVTSNVTAPALIIVGALMVAPLGKIAWDKFEVAVPAFLTMIMMPLTYSIATGIAIGFIFYPITMVCKGKAKEVHPIMYGLFVVFILYFIFLK 4YZF Chain:A ((384-801)) ----RDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEK----TRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPL-LVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEG-SFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTY----LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQ--KLSVPDGFKV--VIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPER--KMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVM--IQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLS------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4YZF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1689 -242366 -143.50 -700.48 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -143.50 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.237

(partial model without unconserved sides chains): PDB file : Tito_4YZF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YZF-query.scw PDB file : Tito_Scwrl_4YZF.pdb: