Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNDFSLELPVRTNKPRETGQSILIDNGYPLQFFKDAIAGASDYIDFVKFGWGTSLLTKDLEEKISTLKEHDITFFFGGTLFEKYVSQKKVNEFHRYCTYFGCEYIEISNGT---LPMTNKEKAAYIADFSD-E---FLVLSEVGSKDAELASRQSSEEWLEYIVEDMEAGAEKVITE-------------------ARESG-TGGICSSSG----DVRFQIVDDIISSDIDINRLIFEAPNKTLQQGFIQKIGPNVNLANIPFHDAIALETLRLGLRSDTFFL 2EHH Chain:A ((18-201)) ------------------------------------------------------------------------------------VDYEALGNLIEFHVDNGTDAILVCGTTGESPTLTFEEHEKVIEFAVKRAAGRIKVIAGTG--------GNATHEAVHLTAHAKEVGADGALVVVPYYNKPTQRGLYEHFKTVAQEVDIPIIIYNIPSRTCVEISVDTMFKLASECENIVASKESTPNMDRISEIVKRLGESFSV--LSGDDSLTLPMMALGAKG-----

General information: TITO was launched using: RESULT: Template: 2EHH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 675 -74997 -111.11 -490.17 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -111.11 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.516

(partial model without unconserved sides chains): PDB file : Tito_2EHH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2EHH-query.scw PDB file : Tito_Scwrl_2EHH.pdb: