Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAQTDYKKQVVGILLSLAFVLFVFSFSERHEKPLVEGKKQENWHTVVDKASVKIYGSRLVEENKLKQKLGHKQADSILTLLKLANEKHITL 2I7U Chain:A ((1-62)) -----------------------------MKKLREEAAKLFEEWKKLAEEAAKLLEGGG-GGGGGELMKLCEEAAKKAEELFKLAEERLKKL

General information: TITO was launched using: RESULT: Template: 2I7U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 106 210 1.98 3.38 target 2D structure prediction score : 0.32 Monomeric hydrophicity matching model chain A : 0.54 3D Compatibility (PKB) : 1.98 2D Compatibility (Sec. Struct. Predict.) : 0.32 1D Compatibility (Hydrophobicity) : 0.54 QMean score : 0.311

(partial model without unconserved sides chains): PDB file : Tito_2I7U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I7U-query.scw PDB file : Tito_Scwrl_2I7U.pdb: