Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MNTAYRVWD----------GEQMHYWDD-EGLSLIIKSNGDWTLKRLYTDVLVPVVDSTNRNAAL-MWGAKV--RGKFIYDRSIVKITSD-DKESSDV-CEVKFSDGVFQVDVSKISADYDVTAVGWVEYATIEVIGDVYQNPELLEGVK 2OX7 Chain:A ((2-145)) SLIPKFRAWDTYEKEMLENVTPLFDDSNSMIAIITDFQIKGSPGTSEIEIGSYDTTFNWDEFPYVIMQSTGLKDKNGVEIFEGDILVYDAPKKYAHRRSMHEIAYADGRFFWEFLDLVFCQSNILYR----DGYLVIGNIHENPELLE---

General information: TITO was launched using: RESULT: Template: 2OX7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 421 7592 18.03 59.78 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 18.03 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.174

(partial model without unconserved sides chains): PDB file : Tito_2OX7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OX7-query.scw PDB file : Tito_Scwrl_2OX7.pdb: