Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFKPFVGVALAALFAVSAVAHAEDAGPVVIKFSHVVSDDTPKGKGALLFKKLAEERLPGKVKVEVYPNSTLFGDADEIEALRANKVQMLATSLSKFEPYTKQLQVFDLPFLFDDLE-ALKRFQKRDKSRELLRSMAKH-GIYGLAYWNNGMKQLSATRELHRPDDAKGLVFRIQPSSVLEAQFAMLGATAKQLSYAETLKAMQAGSVQGTENTWSNLAGQKIDSVQPYITETNHGALSYMLITSSAFWTGIPYQTRTELESIVDEVTLVVNKEAEALNQKEREHLLAAGKSRLVSLSAEEHEAWRNAMKPLWKNYEAQIGSDVLRAAQVVNRKR 2XWK Chain:A ((5-291)) -----------------------------LKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRAMLKQLKDGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSIADMKGLKLAVPNAATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYLVSNETYKELP----EDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTG--------------

General information: TITO was launched using: RESULT: Template: 2XWK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -59665 for 2485 contacts (-24.0/contact) + 2D Compatibility (PS) -30518 + (NN) -14906 + (LL) 4448 1D Compatibility (HY) -14000 + (ID) 3250 Total energy: -117891.0 ( -47.44 by residue) QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_2XWK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XWK-query.scw PDB file : Tito_Scwrl_2XWK.pdb: