Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTQFLGEFLGTFILVLLGDGVVAGNVLSKTKEEGTGWTAIVFGWGIACTVAVYVSGLFSPAHLNPAVTLAMASIGAISWGQVIPFIIAQMLGAMVAATILWLHYYPHWKETKDSGLIL----------ASFST--GPAIRHTPSNLLGEIIGTAILVITIMAI---GPSKVAAGLGPIIVGIVIFAVGFSLGPTTGYAINPARDLGPRLMHAILPIEN---KGDSDWSYAWIPVVGPIIGGVLGAILYNIALTLI 1FX8 Chain:A ((10-252)) --QCIAEFLGTGLLIFFGVGCVAA---LKVAGASFGQWEISVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAALVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAV-EMVITAILMGLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAGWGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRH

General information: TITO was launched using: RESULT: Template: 1FX8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -172410 for 1940 contacts (-88.9/contact) + 2D Compatibility (PS) -22917 + (NN) -1278 + (LL) 376 1D Compatibility (HY) -26800 + (ID) 4200 Total energy: -227229.0 ( -117.13 by residue) QMean score : 0.234

(partial model without unconserved sides chains): PDB file : Tito_1FX8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FX8-query.scw PDB file : Tito_Scwrl_1FX8.pdb: