Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFQIDLNCDLGESFGAYKIGLDQDILEYVTSANIACGFHAGDPSVMRKTVALAAERGVKMGAHPGLPDLLGFGRRNMAISPEEAYDLVVYQIGALSGFLKAEGLHMQHVKPHGALYNMAAVDQKLSDAIAKAVYKVDPGLILFGLAESELVKAGERIGLQTANEVFADRTYQSDGTLTPRSQPDALIESDDAAVTQVIKMVKEGAVKSQQGHDVSLKADTVCIHGDGAHALTFAQKIRKQLKAAGIEVTAISEQRST 1XW8 Chain:A ((2-245)) --KIDLNADLGEGCAS-----DAELLTLVSSANIACGFHAGDAQIMQACVREAIKNGVAIGAHPSFP-------SAMQLPPETVYAQTLYQIGALATIARAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGKQYGLTTREEVFADRGYQADGSLVPRSQSG-----EEQALAQTLEMVQHGRVKSITGEWATVAAQTVCLHGDG-HALAFARRLRSAF----IVVAAL------

General information: TITO was launched using: RESULT: Template: 1XW8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1273 -117916 -92.63 -519.45 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : -92.63 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.562

(partial model without unconserved sides chains): PDB file : Tito_1XW8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XW8-query.scw PDB file : Tito_Scwrl_1XW8.pdb: