Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTHIAWASACLLLVMLTGFFTIGQQTYKIEKLKDKNEVLSEKIKELNHIESTSSASENKAFFEAFFNYSD-------IDIRYET-VKKHTTGKGFDYAFPSRSDQKHTVSVQSELLSLESYSKPLDESHELFLNIVEVATTANSVTTNQVLIVQTTMKKEKDGWLVDNVQVKGNG 2VZ9 Chain:A ((1697-1758)) ---------------------------------------------------TTVGSAEKRAYLQARFPQLDETCFANSRDTSFEQHVLRHTAGKGVDLVLNSLAEEKLQASVR---------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2VZ9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 94 1515 16.11 28.05 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : 16.11 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.313

(partial model without unconserved sides chains): PDB file : Tito_2VZ9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VZ9-query.scw PDB file : Tito_Scwrl_2VZ9.pdb: