Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTALLVIDIQNDYFPNGKMALTNPEKAAQNAAKLLSHFRNTGAPVFHVQHIT-EGNIAHFFHPNTEGVEIHESVRPLEKETVIVKHMPNSFFNTDLNGKLQEEGVKELVVCGMMSHMCIDATVRSAVEHGYVCQVVEDACAT-TTLQIEDKIVPAEHVHYAFMAALNGVYATVKTTEAFLK 3MCW Chain:A ((15-181)) ----LLLIDMQQ-AVDDPSWGPRNHPQAEQACAGLLQAWRARGLPLIHIRHDSVEPN--STYRPGQPGHAFKPEVEPRPGETVIAKQTNSAFIGTGLEALLRANGWLELVVAGVSTSNSVEATVRMAGNLGFAVCLAEDGCFTFDKTDWHGRRRSADEVHAMSLANLDGEYCRV--------

General information: TITO was launched using: RESULT: Template: 3MCW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 808 -104471 -129.30 -633.15 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -129.30 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_3MCW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MCW-query.scw PDB file : Tito_Scwrl_3MCW.pdb: