Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGRKWNNIKEKKASKDANTSRIYAKFGREIYVAAKQGEPDPESNQALKVVLERAKTYSVPKNIIERAIEKAKGGAEE-NYDELRYEGFGPNGSMIIVDALTNNVNRTAPEVRAAFGKNGGNMGVSGSVAYMFDATAVIGVEGKTADEALEILMEADVDVRDILEEDDSAI-VYAEPDQFHAVQEAFKNAGVEEFTVAELTMLAQSEVTLPDDAKEQFEKLIDALEDLEDVQQVYHNVDLGE 1KON Chain:A ((6-235)) ---KWANTRHRKAAQDAKRGKIFTKIIRELVTAAKL-----DANPRLRAAVDKALSNNMTRDTLNRAIARG------ANMETIIYEGYGPGGTAIMIECLSDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE--DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADS-AEVSMIPSTKADMDAETAPKLMRLIDMLEDCDDVQEVYHN-----

General information: TITO was launched using: RESULT: Template: 1KON.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 994 -55787 -56.12 -257.08 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -56.12 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.476

(partial model without unconserved sides chains): PDB file : Tito_1KON.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KON-query.scw PDB file : Tito_Scwrl_1KON.pdb: